Origin BioMedicinals Inc. and its partner, Mitsui Norin & Co. Ltd., Tokyo, are now providing an exclusive weight loss program to the North America marketplace based on clinical trials performed in Japan. The results announced in 2003 are clear: 10% of body fat was lost in 3 months by taking 600 mg per day of Polyphenon green tea catechins. These trial results were so convincing that weight loss claims have now been approved by the Japanese regulatory authority. For the first time, Polyphenon brand catechins are now available to the North American public for weight loss.

Polyphenon 100 Weight Loss Program

Origin BioMedicinals Inc. recommends taking six Polyphenon 100 capsules per day (600 mg catechins) for 3 months. Take 2 capsules approx. 1/2 hour prior to each meal. Very heavy individuals may wish to take up to eight capsules per day. Two bottles of Polyphenon 100 capsules are required per month (90 caps/bottle). During the program, Origin recommends that you eat sensibly and maintain regular exercise. Green tea catechins, a class of polyphenols, are known to provide weight loss by increasing the metabolism of fats by the liver (thermogenic effect), inhibiting lipase (fat absorption enzyme) in the digestive tract, and providing a feeling of satiety and fullness. Catechins do not function as a stimulant. During the Polyphenon weight loss program, you will also receive the many other health-promoting benefits which are being reported for green tea catechins.

Scientific Background for Weight Loss

Five independent clinical trials with a total of 500 subjects have documented that Polyphenon green tea catechins have reduced body weight, especially abdominal body fat. These results were even more dramatic in obese subjects, who observed a greater reduction. In one particular double-blind study involving 80 subjects, the Polyphenon treatment group received 588 catechins daily and showed a significant (P<0.01) weight loss of 1.7Kg in 12 weeks (Figure 1). A separate study conducted in Switzerland supported these results (Dullo, et al. 1999). This study found that green tea weight loss programs can raise metabolic rates and speed up fat oxidation. Compared with placebo and caffeine alone, subjects taking green tea extracts have a significant increase in daily energy expenditure. The study noted that "green tea is superior to stimulant diet drugs, which can have adverse cardiac effects, especially in obese individuals with hypertension and other cardiovascular complications."

Polyphenon Decreases Abdominal Fat

Excess abdominal fat is associated with high cholesterol and an increased risk of heart disease and stroke. In another Polyphenon study, healthy male and female subjects were given 500-600 mg per day of Polyphenon catechins delivered in beverage format over 12 weeks without any dietary restriction. Polyphenon significantly (P<0.01) reduced abdominal fat, as measured by CT scan (Figure 2). Other studies support these findings. In a study of 1200 Taiwanese adults, adults who consumed tea more than once a week for six months had 19.6% less body fat and a 2.1% reduction in waist to hip ratio compared to non-tea drinkers (Wu, 2003). Another study found a significant decrease in body weight, body mass index, waist circumference, body fat ratio, abdominal fat, glucose, insulin and total cholestrol in a group of 23 healthy adult males who took 483 mg catechins per day over a twelve week period (Hase 2001). In those who took 118 mg daily, only weight, body mass index and insulin had changed.

Polyphenon Brand - the Medical Standard

Polyphenon brand green tea catechins are recognized by medical researchers worldwide. For example, the US National Institute of Health and other prestigious medical research organizations have selected Polyphenon catechins to use in their clinical trials for a range of diseases conditions (including cancers and infectious diseases). Polyphenon extracts are also now completing Phase III clinical trials with the US FDA. Polyphenon brand is quickly becoming the recognized medical-quality source of green tea catechins. Polyphenon 100 capsules contain a high-purity, decaffeinated green tea extract derived from carefully selected tea leaves, and a superior extraction and refinement process. Each capsule contains 100 mg catechins (53.7% EGCg), suitable for professional prescription for a variety of therapy regimes.

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